Any hydrocarbon or heterocycle with 4n+2 electrons in a fully conjugated cyclic π system is considered to be an...
Buchler Glossary
Aminohydroxylation
The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes with salts of N-halosulfonamides, -amides and -carbamates using OsO4 as a catalyst. Enantioselectivity is achieved through the addition of Dihydroquinine– and Dihydroquinidine-derived chiral ligands.
Please find some examples of Aminohydroxylation promoted by Cinchona Alkaloids in our Buchler Chiral Catalyst Search.
Example from literature
Imido-osmium(VIII) compounds in organic synthesis: aminohydroxylation and diamination reactions. (Muñiz et al.; Chem. Soc. Rev. 2004, 33, 166-174.)
Further Articles:
Asymmetric Aldol Reaction
The aldol reaction is one of the most important and effective methodologies for the straightforward construction of...
Asymmetric Alkylation
Alkylation is the introduction of an alkyl group into an organic compound by substitution or addition. The alkyl group...
Asymmetric Amination
Amination is the process by which an amine group is introduced into an organic molecule. This type of reaction is...
Asymmetric Dihydroxylation
Asymmetric Dihydroxylation of olefins is of high synthetic value because it introduces two vicinal hydroxy groups,...