Chiral Thiourea-Catalyzed Asymmetric Michael Addition of β-Oxo Phosphonate to Nitro Olefins: Convenient Synthesis of Optically Active β-Oxo Phosphonates.
DOI Number:
10.1002/ejoc.201100029
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
Diethyl P-(2-oxo-2-phenylethyl)phosphonate, 1-Methoxy-2-[(1E)-2-nitroethenyl]benzene
Product:
Diethyl P-[(1R,2R)-1-benzoyl-2-(2-methoxyphenyl)-3-nitropropyl]phosphonate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9R)-cinchonan-9-ylthiourea
Cas No:
901122-96-1
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2