Bicarbonate-binding catalysis for the enantioselective desymmetrization of keto sulfonium salts.

DOI Number:

10.1038/s41467-024-48832-x
Link to literature

Reaction Category:

Desymmetrization

Educt:

(2α,6α)-tetrahydro-1-methyl-4-oxo-2,6-diphenyl-2H-Thiopyranium tetrafluoroborate(1-)

Product:

(R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-86-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2