Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeEpoxidation Oxa-Michael, substituted 3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluoro-1-(naphthalen-1-yl)but-2-en-1-one, hydroxylamine, isoxazoline compound, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris(phenylmethoxy)phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Oxa-Michael, tert-butyl (E)-5′-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-3’H-spiro[azetidine-3,1′-isobenzofuran]-1-carboxylate, hydroxylamine, spirocyclic isooxazolines, (8α,9R)-1-(9-acridinylmethyl)-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition Epoxidation, tert-butyldimethyl(((8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2′-[1,3]dioxolan]-17-yl)oxy)silane, hydrogen peroxide, tert-butyldimethyl(((5’R,8’S,10’R,13’S,14’S,17’S)-13′-methyl-17′-(prop-1-yn-1-yl)-1′,2′,7′,8′,12′,13′,14′,15′,16′,17′-decahydro-4’H,6’H-spiro[[1,3]dioxolane-2,3′-[5,10]epoxycyclopenta[a]phenanthren]-17′-yl)oxy)silane, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinine DerivativeEpoxidation Oxa-Michael, (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzamide, hydroxylamine, isoxazoline compounds, (8α,9R)-1-(9-acridinylmethyl)-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Aminohydroxylation, (E)-1-(4-methoxyphenyl)-4-methylpent-1-en-3-one, N-bromoacetamide, N-((1S,2R)-2-hydroxy-1-(4-methoxyphenyl)-4-methyl-3-oxopentyl)acetamide, silica gel-supported (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan, Dihydroquinine DerivativeAminohydroxylation, Further reactions Flow Chemistry, α,β-unsaturated ketones, carbon with two electron-withdrawing groups, β-substituted ketones, Immobilized (8α,9S)-6′-methoxy-3-(1H-1,2,3-triazol-4-yl)-10,11-dinorcinchonan-9-amine, Quinine DerivativeFlow Chemistry, Michael, Michael Addition Strecker reaction, isatin N‐protected ketimines, trimethylsilanecarbonitrile, N-protected (1R)-1-amino-3-methyl-2-oxo-2,3-dihydro-1H-indene-1-carbonitrile, Immobilized N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Vinylogous Aldol reaction, pyrazole-4,5-diones, allyl ketones, substituted (R,E)-4-hydroxy-4-(4-oxopent-2-en-1-yl)-2,4-dihydro-3H-pyrazol-3-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Vinylogous Aldol« Older EntriesNext Entries »
Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeEpoxidation
Oxa-Michael, substituted 3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluoro-1-(naphthalen-1-yl)but-2-en-1-one, hydroxylamine, isoxazoline compound, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris(phenylmethoxy)phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Oxa-Michael, tert-butyl (E)-5′-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-3’H-spiro[azetidine-3,1′-isobenzofuran]-1-carboxylate, hydroxylamine, spirocyclic isooxazolines, (8α,9R)-1-(9-acridinylmethyl)-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition
Epoxidation, tert-butyldimethyl(((8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2′-[1,3]dioxolan]-17-yl)oxy)silane, hydrogen peroxide, tert-butyldimethyl(((5’R,8’S,10’R,13’S,14’S,17’S)-13′-methyl-17′-(prop-1-yn-1-yl)-1′,2′,7′,8′,12′,13′,14′,15′,16′,17′-decahydro-4’H,6’H-spiro[[1,3]dioxolane-2,3′-[5,10]epoxycyclopenta[a]phenanthren]-17′-yl)oxy)silane, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinine DerivativeEpoxidation
Oxa-Michael, (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzamide, hydroxylamine, isoxazoline compounds, (8α,9R)-1-(9-acridinylmethyl)-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Aminohydroxylation, (E)-1-(4-methoxyphenyl)-4-methylpent-1-en-3-one, N-bromoacetamide, N-((1S,2R)-2-hydroxy-1-(4-methoxyphenyl)-4-methyl-3-oxopentyl)acetamide, silica gel-supported (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan, Dihydroquinine DerivativeAminohydroxylation, Further reactions
Flow Chemistry, α,β-unsaturated ketones, carbon with two electron-withdrawing groups, β-substituted ketones, Immobilized (8α,9S)-6′-methoxy-3-(1H-1,2,3-triazol-4-yl)-10,11-dinorcinchonan-9-amine, Quinine DerivativeFlow Chemistry, Michael, Michael Addition
Strecker reaction, isatin N‐protected ketimines, trimethylsilanecarbonitrile, N-protected (1R)-1-amino-3-methyl-2-oxo-2,3-dihydro-1H-indene-1-carbonitrile, Immobilized N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Vinylogous Aldol reaction, pyrazole-4,5-diones, allyl ketones, substituted (R,E)-4-hydroxy-4-(4-oxopent-2-en-1-yl)-2,4-dihydro-3H-pyrazol-3-one, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)-benzamide, Quinine DerivativeAldol, Vinylogous Aldol
