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Atropisomer synthesis, 2-arylimidazoles, Morita–Baylis–Hillman (MBH) carbonates, arylimidazoles, Quinidine Base

Atropisomer synthesis

Chlorination, (Z)-3-((5-hydroxy-1,3-diphenyl-1H-pyrazol-4-yl)methylene)-1-methylindolin-2-one, N-chlorosuccinimide, (S,Z)-3-((4-chloro-5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-yl)methylene)-1-methylindolin-2-one, Quinidine Base

Chlorination

Mannich reaction, α-aminomaleimides, benzothiazolimines, substituted 3-amino-4-((benzo[d]thiazol-2-ylamino)methyl)-1H-pyrrole-2,5-dione, copper(II) triflate, N-[2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-4-pyridinyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative

Mannich, Mannich

Mannich reaction, tert-butyl ((4H-spiro[benzo[d][1,3]dioxine-2,1′-cyclohexan]-7-yl)methylene)carbamate, 5-hydroxy-2-methyl-4H-pyran-4-one, tert-butyl (S)-((3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)(4H-spiro[benzo[d][1,3]dioxine-2,1′-cyclohexan]-7-yl)methyl)carbamate, Dihydroquinine Base

Mannich, Mannich

Amination, 3,5-dihalogen BODIPYs, benzamide, BODIPYs, N-[3,5-bis(trifluoromethyl)benzyl]-quininium Bromide, Quinine Derivative

Allylic Amination, Amination

Mannich reaction, α-benzylidene succinimides, Imines, substituted 3-(aminomethyl)-4-methylenepyrrolidine-2,5-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Mannich, Mannich

Cascade reaction, 1-phenethylindoline-2,3-dione, 2-cyclohexenone, diethyl phosphonate, diethyl ((S)-2-oxo-3-((S)-3-oxocyclohexyl)-1-phenethylindolin-3-yl) phosphate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Cascade reaction

Michael Addition, β‐ketosulfones, nitroalkenes, 4-nitro-1,3-diphenyl-2-(phenylsulfonyl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

Michael Addition, 2‐hydroxybenzylidene ketones, α‐nitroketones, substituted (S)-2-(1-nitro-4-oxobutan-2-yl)phenyl formate, (8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine, Dihydroquinine Derivative

Michael, Michael Addition

Vinylogous Michael Addition, 2-(thiochroman-4-ylidene)malononitrile, (E)-(2-nitrovinyl)benzene, 2-((S)-3-((R)-2-nitro-1-phenylethyl)thiochroman-4-ylidene)malononitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael Addition, Vinylogous Michael Addition

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