Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition Michael Addition, 3-aryloxindoles, vinyl bisphosphonate ester, 3-(bisphosphonate ester)-3-aryloxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, 3-alkylthiooxindoles, nitroolefins, 3-alkylthio-3-(2-nitroethyl)-oxindoles, Bis(1-ethylpropyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, alpha,beta unsaturated nitroalkenes, acetone, 4-substituted 5-nitropentan-2-one, 1-((R)-2-hydroxy-1-phenylethyl)-3-((S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonidine DerivativeMichael, Michael Addition Trifluoromethylation, substituted allyl compound, trimethyl(trifluoromethyl)silane, allyl trifluoromethane, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoromethylation Fluoromethylation, allyl fluorides, trimethyl(perfluorophenyl)silane, allyl fluorides, allyl pentafluorobenzene, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFluorination, Fluoromethylation Aza-Michael Addition, methyl (2E)-3-(3-fluoro-2-((((2-methoxy-5-(trifluoromethyl)phenyl)amino)(4-(3-methoxyphenyl)piperazin-1-yl)methylene)amino)phenyl)acrylate, methyl (S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)benzyl]-N’-[3-(trifluoromethyl)benzyl]-cinchonidinium Bromide, Cinchonidine DerivativeAza-Michael, Michael Addition Fluoromethylation, N-Boc α-phenylsulfonyl amines, (fluoromethylenedisulfonyl)dibenzene, N-Boc α-fluorobisphenylsulfonyl amines, N-Benzylquinidinium Chloride, Quinidine DerivativeFluorination, Fluoromethylation Fluorination, 2-(4-methoxyphenyl)acetyl chloride, tert-butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide, tert-butyl (S)-2-(((R)-2-fluoro-2-(4-methoxyphenyl)acetoxy)methyl)pyrrolidine-1-carboxylate, Dichloro[1,3-bis(diphenylphosphino)propane]nickel, 6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate, Quinidine Derivativealpha-Fluorination, Fluorination Trifluoromethylthiolation, tert-butyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, N-Trifluoromethylthiophthalimide, tert-butyl (S)-1-oxo-2-((trifluoromethyl)thio)-2,3-dihydro-1H-indene-2-carboxylate, Quinidine BaseTrifluoro-methylthiolation« Older EntriesNext Entries »
Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition
Michael Addition, 3-aryloxindoles, vinyl bisphosphonate ester, 3-(bisphosphonate ester)-3-aryloxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, 3-alkylthiooxindoles, nitroolefins, 3-alkylthio-3-(2-nitroethyl)-oxindoles, Bis(1-ethylpropyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, alpha,beta unsaturated nitroalkenes, acetone, 4-substituted 5-nitropentan-2-one, 1-((R)-2-hydroxy-1-phenylethyl)-3-((S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonidine DerivativeMichael, Michael Addition
Trifluoromethylation, substituted allyl compound, trimethyl(trifluoromethyl)silane, allyl trifluoromethane, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoromethylation
Fluoromethylation, allyl fluorides, trimethyl(perfluorophenyl)silane, allyl fluorides, allyl pentafluorobenzene, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFluorination, Fluoromethylation
Aza-Michael Addition, methyl (2E)-3-(3-fluoro-2-((((2-methoxy-5-(trifluoromethyl)phenyl)amino)(4-(3-methoxyphenyl)piperazin-1-yl)methylene)amino)phenyl)acrylate, methyl (S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate, N-[3,5-bis(trifluoromethyl)benzyl]-N’-[3-(trifluoromethyl)benzyl]-cinchonidinium Bromide, Cinchonidine DerivativeAza-Michael, Michael Addition
Fluoromethylation, N-Boc α-phenylsulfonyl amines, (fluoromethylenedisulfonyl)dibenzene, N-Boc α-fluorobisphenylsulfonyl amines, N-Benzylquinidinium Chloride, Quinidine DerivativeFluorination, Fluoromethylation
Fluorination, 2-(4-methoxyphenyl)acetyl chloride, tert-butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide, tert-butyl (S)-2-(((R)-2-fluoro-2-(4-methoxyphenyl)acetoxy)methyl)pyrrolidine-1-carboxylate, Dichloro[1,3-bis(diphenylphosphino)propane]nickel, 6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate, Quinidine Derivativealpha-Fluorination, Fluorination
Trifluoromethylthiolation, tert-butyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, N-Trifluoromethylthiophthalimide, tert-butyl (S)-1-oxo-2-((trifluoromethyl)thio)-2,3-dihydro-1H-indene-2-carboxylate, Quinidine BaseTrifluoro-methylthiolation
