Domino Michael – Alkylation, methyleneindolinones, gamma-halogenated-beta-ketoesters, spiro-cyclopentanoneoxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction, Cyclization Michael Addition, 2-oxindoles, vinyl selenone, 3-(2-(phenylselenonyl)ethyl)indolin-2-ones, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition Michael Addition, 3-aryloxindoles, vinyl bisphosphonate ester, 3-(bisphosphonate ester)-3-aryloxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, 3-alkylthiooxindoles, nitroolefins, 3-alkylthio-3-(2-nitroethyl)-oxindoles, Bis(1-ethylpropyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, alpha,beta unsaturated nitroalkenes, acetone, 4-substituted 5-nitropentan-2-one, 1-((R)-2-hydroxy-1-phenylethyl)-3-((S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonidine DerivativeMichael, Michael Addition Trifluoromethylation, substituted allyl compound, trimethyl(trifluoromethyl)silane, allyl trifluoromethane, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoromethylation Fluoromethylation, allyl fluorides, trimethyl(perfluorophenyl)silane, allyl fluorides, allyl pentafluorobenzene, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFluorination, Fluoromethylation Aza-Michael Addition, methyl (2E)-3-(3-fluoro-2-((((2-methoxy-5-(trifluoromethyl)phenyl)amino)(4-(3-methoxyphenyl)piperazin-1-yl)methylene)amino)phenyl)acrylate, methyl (S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate, (1S,2S,4S,5R)-1-(3,5-bis(trifluoromethyl)benzyl)-2-((R)-hydroxy(1-(3-(trifluoromethyl)benzyl)quinolin-1-ium-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAza-Michael, Michael Addition Fluoromethylation, N-Boc α-phenylsulfonyl amines, (fluoromethylenedisulfonyl)dibenzene, N-Boc α-fluorobisphenylsulfonyl amines, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-Cinchonanium chloride (1:1), Quinidine DerivativeFluorination, Fluoromethylation« Older EntriesNext Entries »
Domino Michael – Alkylation, methyleneindolinones, gamma-halogenated-beta-ketoesters, spiro-cyclopentanoneoxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCascade reaction, Cyclization
Michael Addition, 2-oxindoles, vinyl selenone, 3-(2-(phenylselenonyl)ethyl)indolin-2-ones, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
Spirocyclization/Diels Alder/Michael Addition, 2-ethylidene-indanedione, alpha,beta unsaturated ketone, indanedione-fused 2,6-disubstituted trans-spirocyclohexanone, indanedione-fused 2,6-disubstituted cis-spirocyclohexanone, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction, Michael, Michael Addition
Michael Addition, 3-aryloxindoles, vinyl bisphosphonate ester, 3-(bisphosphonate ester)-3-aryloxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, 3-alkylthiooxindoles, nitroolefins, 3-alkylthio-3-(2-nitroethyl)-oxindoles, Bis(1-ethylpropyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, alpha,beta unsaturated nitroalkenes, acetone, 4-substituted 5-nitropentan-2-one, 1-((R)-2-hydroxy-1-phenylethyl)-3-((S)-quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonidine DerivativeMichael, Michael Addition
Trifluoromethylation, substituted allyl compound, trimethyl(trifluoromethyl)silane, allyl trifluoromethane, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeTrifluoromethylation
Fluoromethylation, allyl fluorides, trimethyl(perfluorophenyl)silane, allyl fluorides, allyl pentafluorobenzene, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFluorination, Fluoromethylation
Aza-Michael Addition, methyl (2E)-3-(3-fluoro-2-((((2-methoxy-5-(trifluoromethyl)phenyl)amino)(4-(3-methoxyphenyl)piperazin-1-yl)methylene)amino)phenyl)acrylate, methyl (S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate, (1S,2S,4S,5R)-1-(3,5-bis(trifluoromethyl)benzyl)-2-((R)-hydroxy(1-(3-(trifluoromethyl)benzyl)quinolin-1-ium-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Cinchonidine DerivativeAza-Michael, Michael Addition
Fluoromethylation, N-Boc α-phenylsulfonyl amines, (fluoromethylenedisulfonyl)dibenzene, N-Boc α-fluorobisphenylsulfonyl amines, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-(9S)-Cinchonanium chloride (1:1), Quinidine DerivativeFluorination, Fluoromethylation
