Michael Addition, nitroalkenes, thiazolones, 2,4,4-trisubstituted thiazolones, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeMichael, Michael Addition Cascade reaction, aldehydes, malononitrile, pyranones, pyranocoumarins, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCascade reaction Mannich reaction, substituted 4-methyl-N-methylenebenzenesulfonamide, 3-(2-isothiocyanatoacetyl)-4,4-dimethyloxazolidin-2-one, cyclic thioureas, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich Spirocyclization, ethyl (E)-2-(5-methyl-2-oxobenzofuran-3(2H)-ylidene)acetate, N-protected 5-fluoro-3-((4-oxo-4H-chromen-3-yl)methyl)indolin-2-one, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeEpoxidation Oxa-Michael, substituted 3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluoro-1-(naphthalen-1-yl)but-2-en-1-one, hydroxylamine, isoxazoline compound, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris(phenylmethoxy)phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Oxa-Michael, tert-butyl (E)-5′-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-3’H-spiro[azetidine-3,1′-isobenzofuran]-1-carboxylate, hydroxylamine, spirocyclic isooxazolines, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition Epoxidation, tert-butyldimethyl(((8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2′-[1,3]dioxolan]-17-yl)oxy)silane, hydrogen peroxide, tert-butyldimethyl(((5’R,8’S,10’R,13’S,14’S,17’S)-13′-methyl-17′-(prop-1-yn-1-yl)-1′,2′,7′,8′,12′,13′,14′,15′,16′,17′-decahydro-4’H,6’H-spiro[[1,3]dioxolane-2,3′-[5,10]epoxycyclopenta[a]phenanthren]-17′-yl)oxy)silane, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinine DerivativeEpoxidation Oxa-Michael, (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzamide, hydroxylamine, isoxazoline compounds, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition« Older EntriesNext Entries »
Michael Addition, nitroalkenes, thiazolones, 2,4,4-trisubstituted thiazolones, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeMichael, Michael Addition
Cascade reaction, aldehydes, malononitrile, pyranones, pyranocoumarins, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCascade reaction
Mannich reaction, substituted 4-methyl-N-methylenebenzenesulfonamide, 3-(2-isothiocyanatoacetyl)-4,4-dimethyloxazolidin-2-one, cyclic thioureas, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich
Spirocyclization, ethyl (E)-2-(5-methyl-2-oxobenzofuran-3(2H)-ylidene)acetate, N-protected 5-fluoro-3-((4-oxo-4H-chromen-3-yl)methyl)indolin-2-one, spirocyclic compound, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization
Epoxidation, (E)-3-(2-fluorophenyl)-1-phenylprop-2-en-1-one, hydrogen peroxide, ((2S,3R)-3-(2-fluorophenyl)oxiran-2-yl)(phenyl)methanone, (8α,9R)-(8′′α,9′′R)-1,1′′-[[2,2-bis[[4-[[(8α,9R)-9-hydroxy-6′-methoxycinchonanium-1-yl]methyl]phenoxy]methyl]-1,3-propanediyl]bis(oxy-4,1-phenylenemethylene)]bis[9-hydroxy-6′-methoxy-cinchonanium bromide, Quinine DerivativeEpoxidation
Oxa-Michael, substituted 3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluoro-1-(naphthalen-1-yl)but-2-en-1-one, hydroxylamine, isoxazoline compound, (8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris(phenylmethoxy)phenyl]methyl]-cinchonanium chloride, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Oxa-Michael, tert-butyl (E)-5′-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-3’H-spiro[azetidine-3,1′-isobenzofuran]-1-carboxylate, hydroxylamine, spirocyclic isooxazolines, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
Michael Addition, tert-butyl (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzoate, 2-hydroxy-2-methylpropanenitrile, tert-butyl (R)-4-(3-cyano-3-(3,5-dichlorophenyl)-4,4,4-trifluorobutanoyl)-2-methylbenzoate, (8α,9R)-1-(9-anthracenylmethyl)-9-hydroxy-6′-methoxy-cinchonanium chloride, Quinine DerivativeMichael, Michael Addition
Epoxidation, tert-butyldimethyl(((8S,13S,14S,17S)-13-methyl-17-(prop-1-yn-1-yl)-1,2,4,6,7,8,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2′-[1,3]dioxolan]-17-yl)oxy)silane, hydrogen peroxide, tert-butyldimethyl(((5’R,8’S,10’R,13’S,14’S,17’S)-13′-methyl-17′-(prop-1-yn-1-yl)-1′,2′,7′,8′,12′,13′,14′,15′,16′,17′-decahydro-4’H,6’H-spiro[[1,3]dioxolane-2,3′-[5,10]epoxycyclopenta[a]phenanthren]-17′-yl)oxy)silane, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium bromide, Quinine DerivativeEpoxidation
Oxa-Michael, (E)-4-(3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl)-2-methylbenzamide, hydroxylamine, isoxazoline compounds, N-(9-Acridinylmethyl)quininium Bromide, Quinine DerivativeCyclization, Isoxazoline cyclization, Michael Addition, Oxa-Michael Addition
