Hydrogenation, α-halogenated ketones, hydrogen, 2-halogen alcohols, iridium catalyst, (S)-N-(2-(diphenylphosphaneyl)benzyl)-1-(6-methoxyquinolin-4-yl)-1-((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine, Quinine DerivativeHydrogenation, Hydrogenation of ketones Mannich reaction, 3-fluorooxindoles, α-amidosulfones, α-fluoro-β-amino-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeMannich, Mannich Cycloaddition, γ-butenolides, ortho-hydroxyphenyl para-quinone methide, (3S,4S)-3-(2-(4-chlorophenyl)-2-oxoethyl)-4-(3,5-di-tert-butyl-4-hydroxyphenyl)chroman-2-one, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition Atropisomer Synthesis, substituted 1-(3-hydrazineylideneprop-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, atropisomeric pyrazoles, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis Cyclization, substituted 3-(2-((2-hydroxynaphthalen-1-yl)ethynyl)phenyl)-5-methyleneoxazolidin-2-one, N-bromosuccinimide, nine‐membered carbonate‐bridged biaryls, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis, Cyclization, Cyclization, Further Cyclizations Atropisomer Synthesis, substituted (2-((2-hydroxynaphthalen-1-yl)ethynyl)phenyl)silanol, N-iodosuccinimide, atropisomeric heterobiaryls, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis Reduction, β-polyfluoro-alkylated enones, (R)-4,4,4-trifluoro-3-phenyl-1-(pyridin-2-yl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeHydrogenation, Reduction Spirocyclization, 2-(1-methyl-2-oxoindolin-3-ylidene)malononitrile, 1-(2-hydroxyphenyl)butane-1,3-dione, spirooxindoles, 1-cyclohexyl-3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Quinine DerivativeSpirocyclization Michael Addition, ethyl 2-cyano-2-(1H-pyrrol-1-yl)acetate, 2-chloroacrylonitrile, ethyl 2,4-dicyano-2-(1H-pyrrol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Cascade reaction, 2-(2-oxoindolin-3-ylidene)malononitrile, methyl pyruvate, spirooxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCascade reaction, Spirocyclization« Older EntriesNext Entries »
Hydrogenation, α-halogenated ketones, hydrogen, 2-halogen alcohols, iridium catalyst, (S)-N-(2-(diphenylphosphaneyl)benzyl)-1-(6-methoxyquinolin-4-yl)-1-((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanamine, Quinine DerivativeHydrogenation, Hydrogenation of ketones
Mannich reaction, 3-fluorooxindoles, α-amidosulfones, α-fluoro-β-amino-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeMannich, Mannich
Cycloaddition, γ-butenolides, ortho-hydroxyphenyl para-quinone methide, (3S,4S)-3-(2-(4-chlorophenyl)-2-oxoethyl)-4-(3,5-di-tert-butyl-4-hydroxyphenyl)chroman-2-one, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[4+2]-Cycloaddition, Cycloaddition
Atropisomer Synthesis, substituted 1-(3-hydrazineylideneprop-1-yn-1-yl)naphthalen-2-ol, N-bromophthalimide, atropisomeric pyrazoles, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis
Cyclization, substituted 3-(2-((2-hydroxynaphthalen-1-yl)ethynyl)phenyl)-5-methyleneoxazolidin-2-one, N-bromosuccinimide, nine‐membered carbonate‐bridged biaryls, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis, Cyclization, Cyclization, Further Cyclizations
Atropisomer Synthesis, substituted (2-((2-hydroxynaphthalen-1-yl)ethynyl)phenyl)silanol, N-iodosuccinimide, atropisomeric heterobiaryls, (2S)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide, Quinine DerivativeAtropisomer synthesis
Reduction, β-polyfluoro-alkylated enones, (R)-4,4,4-trifluoro-3-phenyl-1-(pyridin-2-yl)butan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeHydrogenation, Reduction
Spirocyclization, 2-(1-methyl-2-oxoindolin-3-ylidene)malononitrile, 1-(2-hydroxyphenyl)butane-1,3-dione, spirooxindoles, 1-cyclohexyl-3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Quinine DerivativeSpirocyclization
Michael Addition, ethyl 2-cyano-2-(1H-pyrrol-1-yl)acetate, 2-chloroacrylonitrile, ethyl 2,4-dicyano-2-(1H-pyrrol-1-yl)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Cascade reaction, 2-(2-oxoindolin-3-ylidene)malononitrile, methyl pyruvate, spirooxindoles, N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]-thiourea, Quinine DerivativeCascade reaction, Spirocyclization
