Ring-Strain-Enabled Catalytic Asymmetric Umpolung C–O Bond-Forming Reactions of 1, 2-Oxazetidines for the Synthesis of Functionalized Chiral Ethers.
DOI Number:
10.1021/acs.orglett.0c01916
Reaction Category:
Educt:
substituted tert-butyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, 3,4-disubstituted-2-((4-nitrophenyl)sulfonyl)-1,2-oxazetidine
Product:
substituted tert-butyl (2S)-2-(1,2-disubstituted-2-((4-nitrophenyl)sulfonamido)ethoxy)-1-oxo-2,3-dihydro-1H-indene-2-carboxylate
Catalyst:
(9S)-1-[[4,4′′-bis(1,1-dimethylethyl)[1,1′:4′,1′′-terphenyl]-2′-yl]methyl]-9-(2,2-dimethyl-1-oxopropoxy)-cinchonanium bromide
Cas No:
2473830-67-8
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5