Asymmetric multicomponent sulfa-Michael/Mannich cascade reaction: synthetic access to 1, 2-diamino-3-organosulfur compounds and 2-nitro allylic amines.
DOI Number:
10.1021/acs.orglett.5b02423
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
arylic thiols, arylic (E)-nitroethene, arylic (E)-4-methyl-N-methylenebenzenesulfonamide
Product:
1,3 substituted N-((1R,2S,3S)-3-(arylthio)-2-nitropropyl)-4-methylbenzenesulfonamide
Catalyst:
N-[(1R,2S)-2-(1,1-dimethylethoxy)-1-[[[[[(8α,9R)-9-(phenylmethoxy)cinchonan-6′-yl]amino]thioxomethyl]amino]methyl]propyl]-4-methyl-benzenesulfonamide
Cas No:
1809547-69-0
Associated Product from Buchler GmbH:
6´-Aminocinchonidine Base
Cas No:
2143936-34-7