The synthesis of chiral β-naphthyl-β-sulfanyl ketones via enantioselective sulfa-Michael reaction in the presence of a bifunctional cinchona/sulfonamide organocatalyst.
DOI Number:
10.3762/bjoc.17.43
Reaction Category:
Educt:
naphthalene-1-thiol, (E)-1-phenyl-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one
Product:
(S)-3-(naphthalen-1-ylthio)-1-phenyl-3-(3,4,5-trimethoxyphenyl)propan-1-one
Catalyst:
N-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-2,4,6-trimethyl-3-nitrobenzenesulfonamide
Cas No:
not found
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0