A novel C-5′ substituted cinchona alkaloid-derived catalyst promotes additions of alkyl thiols to nitroolefins with excellent enantioselectivity.
DOI Number:
10.1039/C2CC17965B
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
(E)-2-(2-nitrovinyl)pyridine, (4-(tert-butyl)phenyl)methanethiol
Product:
(R)-2-(1-((4-(tert-butyl)benzyl)thio)-2-nitroethyl)pyridine
Catalyst:
N-[3,5-bis(trifluoromethyl)phenyl]-N-[(8α,9R)-9-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea
Cas No:
1362113-49-2
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7