Sulfa-Michael Addition, alpha,beta-unsaturated N-acylated succinimides, thiols, beta-sulfated thioester derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Chiral squaramide-catalysed one-pot enantioselective sulfa-Michael addition/thioesterification of thiols with α, β-unsaturated N-acylated succinimides.

DOI Number:

10.1039/C3OB42137F

Link to literature

Reaction Category:

Michael Addition | Sulfa-Michael | Sulfa-Michael Addition

RXNO ID:

RXNO_0000009

Educt:

alpha,beta-unsaturated N-acylated succinimides, thiols

Product:

beta-sulfated thioester derivatives

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

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Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0