Enantioselective Strecker-type reaction between azomethine imines and trimethylsilyl cyanide catalyzed by a cinchona alkaloid-derived thiourea bearing multiple hydrogen-bonding donors.

DOI Number:

10.1039/C3RA41640B

Reaction Category:

Educt:

azomethine imines, trimethylsilyl cyanide

Product:

(S)-2-(3-oxopyrazolidin-1-yl)-2-Arylacetonitrile

Catalyst:

N-[(1S,2R)-2-hydroxy-1,2-diphenylethyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea

Cas No:

1491173-70-6

Cas No:

130-95-0