A cinchona alkaloid catalyzed enantioselective sulfa-Michael/aldol cascade reaction of isoindigos: construction of chiral bispirooxindole tetrahydrothiophenes with vicinal quaternary spirocenters.
DOI Number:
10.1039/c5ob00774g
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
1,4-dithiane-2,5-diol, N/C-substituted-(E)-[3,3'-biindolinylidene]-2,2'-dione
Product:
N/C-substituted-(3S,3'R,4'R)-4'-hydroxy-4',5'-dihydrodispiro[indoline-3,2'-thiophene-3',3''-indoline]-2,2''-dione
Catalyst:
Quinine Base
Cas No:
130-95-0
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0