Observation of neighboring ortho-hydroxyl group participation in organocatalytic asymmetric sequential Michael-lactonization reactions: synthesis of highly substituted chiral spirodihydrocoumarins.
DOI Number:
10.1039/C2OB07122C
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
substituted (E)-2-(2-nitrovinyl)phenol, 2-oxocyclopentane-1-carboxylates
Product:
spirodihydrocoumarins, (9R,9aS)-9-(nitromethyl)-1,2-dihydrocyclopenta[b]chromene-9a(9H)-carboxylates
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7