Highly organocatalytic asymmetric Michael–ketone aldol–dehydration domino reaction: straightforward approach to construct six-membered spirocyclic oxindoles.
DOI Number:
10.1039/C0CC03032E
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
N-substituted 1-(2-hydroxy-1H-indol-3-yl)ethan-1-one, alpha,beta-unsaturated methylketones
Product:
six-membered spirocyclic oxindoles
Catalyst:
(9R)-Cinchonan-9-amine
Cas No:
168960-96-1
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5