Stereoselective construction of Bi-spirooxindole frameworks via a Michael addition/cyclization and an unexpected redox/oxidative coupling/cyclization.

DOI Number:

10.1016/j.tet.2016.11.001

Reaction Category:

MOP ID:

MOP_0000561

Educt:

N/C-substituted 2-(2-oxoindolin-3-ylidene)malononitrile, N/C-Substituted 3-hydroxyindolin-2-one

Product:

N/C-subsituted 5'-amino-2,2''-dioxodispiro[indoline-3,2'-furan-3',3''-indoline]-4'-carbonitrile

Catalyst:

Cinchonine Base

Cas No:

118-10-5

Cas No:

118-10-5