Organocatalyzed Cascade Aza-Michael/Michael Addition for the Asymmetric Construction of Highly Functionalized Spiropyrazolone Tetrahydroquinolines.

DOI Number:

10.1002/asia.201402706
Link to literature

Reaction Category:

Cascade reaction | Spirocyclization

Educt:

4-alkylidene-2,4-dihydro-3H-pyrazol-3-one, alpha,beta unsaturated ketones

Product:

Spiropyrazolone Tetrahydroquinolines

Catalyst:

3-[[(9R)-6′-Methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-80-3

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2