The cinchona alkaloid squaramide catalyzed asymmetric Pictet–Spengler reaction and related theoretical studies.

DOI Number:

10.1039/c7ob02606d

Reaction Category:

MOP ID:

MOP_0000561

Educt:

2-(1H-indol-3-yl)-N-(naphthalen-2-ylmethyl)ethan-1-amine, benzaldehyde

Product:

(R)-2-(naphthalen-2-ylmethyl)-1-phenyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0