Asymmetric synthesis of 1,3-dioxolanes by organocatalytic formal [3+2] cycloaddition via hemiacetal intermediates.

DOI Number:

10.1021/ol3003755
Link to literature

Reaction Category:

[3+2]-Cycloaddition | Cycloaddition | Michael Addition | Oxa-Michael Addition

MOP ID:

MOP_0000715

Educt:

γ-hydroxy-α,β-unsaturated ketones, ketones

Product:

1,3-dioxolanes

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8