Synthesis of Atropisomeric Hydrazides by One-Pot Sequential Enantio- and Diastereoselective Catalysis.

DOI Number:

10.1002/anie.202209895
Link to literature

Reaction Category:

Atropisomer synthesis

Educt:

2-phenylpropanal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, (bromomethyl)benzene

Product:

di-tert-butyl (S)-1-benzyl-2-(1-oxo-2-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate

Catalyst:

(8α,9S)-6′-Methoxycinchonan-9-amine, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide

Cas No:

168960-95-0, 69212-47-1

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0