Highly efficient and enantioselective Michael addition of acetylacetone to nitroolefins catalyzed by chiral bifunctional organocatalyst bearing multiple hydrogen-bonding donors.
DOI Number:
10.1016/j.tetlet.2011.04.043
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
nitroolefines, pentane-2,4-dione
Product:
3-(1-substituted-2-nitroethyl)pentane-2,4-dione
Catalyst:
N-[(1R)-1-(hydroxymethyl)-2-methylpropyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea
Cas No:
1333118-03-8
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0