Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL–quinine–squaramide: efficient access to optically active nitro-alkanes and their isoxazole derivatives.

DOI Number:

10.1016/j.tetasy.2013.08.010

Reaction Category:

Educt:

nitroalkenes, 1,3-dicarbonyl compounds

Product:

nitroalkanes

Catalyst:

3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1486483-03-7

Cas No:

130-95-0