Mechanism and origins of stereoselectivity in the cinchona thiourea- and squaramide-catalyzed asymmetric Michael addition of nitroalkanes to enones.

DOI Number:

10.1021/acs.joc.7b00521

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

(E)-chalcone, nitromethane

Product:

(R)-4-nitro-1,3-diphenylbutan-1-one

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Cas No:

522-66-7