Asymmetric Organocatalysis and Continuous Chemistry for an Efficient and Cost-Competitive Process to Pregabalin.
DOI Number:
10.1021/acs.oprd.1c00394
Reaction Category:
Educt:
(E)-4-methyl-1-nitropent-1-ene, dimethyl malonate
Product:
dimethyl (S)-2-(4-methyl-1-nitropentan-2-yl)malonate
Catalyst:
3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione
Cas No:
1431159-77-1
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2