Highly enantioselective synthesis of chiral 7-ring O-and N-heterocycles by a one-pot nitro-Michael–cyclization tandem reaction.

DOI Number:

10.1039/C3CC47397J

Reaction Category:

MOP ID:

MOP_0000561

Educt:

(E)-2-(allyloxy)-1-methoxy-3-(2-nitrovinyl)benzene, dimethyl malonate

Product:

7-ring O-heterocycles

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8