Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts.

DOI Number:

10.1021/ol102294g

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

chalcones, nitromethane

Product:

1,3-disubstituted 4-nitrobutan-1-one

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-79-0

Cas No:

56-54-2