Construction of Nonadjacent Stereocenters Containing a Trifluoromethylated Carbon by Organocatalyzed Michael Addition of β-Ketoesters to 2-(Trifluoromethyl)acrylate
DOI Number:
10.1246/cl.2009.1006
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
beta-ketoester, tert-butyl 2-(trifluoromethyl)acrylate
Product:
5-(tert-butyl) 1-substituted (S)-2-substitutedcarbonyl-2-substituted-4-(trifluoromethyl)-4lambda3-pentanedioate
Catalyst:
Cinchonine Base
Cas No:
118-10-5
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5