Cinchona-based primary amine-catalyzed enantioselective aza-Michael reactions of pyrroles with α,β-unsaturated aldehydes.

DOI Number:

10.1016/j.tetasy.2014.09.002

Reaction Category:

Educt:

4,5-dihalo-1H-pyrrole-2-carbonitriles, α,β-unsaturated aldehydes

Product:

4,5-dihalo-1-(1-substituted-3-hydroxypropyl)-1H-pyrrole-2-carbonitrile

Catalyst:

(8α,9S)-6′-Methoxycinchonan-9-amine

Cas No:

168960-95-0

Cas No:

130-95-0