Catalytic Enantioselective Michael Addition of 1-Fluorobis(phenylsulfonyl)methane to α,β-Unsaturated Ketones Catalyzed by Cinchona Alkaloid.
DOI Number:
10.1002/anie.200802904
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
1-Fluorobis(phenylsulfonyl)methane, (E)-3-(3-chlorophenyl)-1-phenylprop-2-en-1-one
Product:
(S)-3-(3-chlorophenyl)-4-fluoro-1-phenyl-4,4-bis(phenylsulfonyl)butan-1-one
Catalyst:
(1S,2R,4S,5R)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-1-((3,3'',5,5''-tetrakis(trifluoromethyl)-[1,1':3',1''-terphenyl]-5'-yl)methyl)-5-vinylquinuclidin-1-ium bromide
Cas No:
1091629-74-1
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2