Organocatalytic enantioselective Michael reaction of 1,3-dicarbonyls with α-substituted β-nitroacrylates.

DOI Number:

10.1016/j.tet.2016.12.039
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

α-substituted β-nitroacrylates, 1,3-dicarbonyls

Product:

ethyl (R)-3-acetyl-2-(4-methoxyphenyl)-2-(nitromethyl)-4-oxopentanoate

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7