Highly enantioselective three-component direct mannich reactions of unfunctionalized ketones catalyzed by bifunctional organocatalysts.
DOI Number:
10.1021/ol303315c
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
unfunctionalized ketones, 4-methylbenzenesulfonamide, substituted benzaldehydes
Product:
substituted (S)-4-methyl-N-(3-oxo-1-phenylpropyl)benzenesulfonamide
Catalyst:
N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]-thiourea
Cas No:
882166-36-1
Associated Product from Buchler GmbH:
6´-Aminocinchonine Base
Cas No:
2143936-31-4