Direct Asymmetric Mannich-Type Reaction of α-Isocyanoacetates with Ketimines using Cinchona Alkaloid/Copper(II) Catalysts.
DOI Number:
10.1002/anie.201404629
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
substituted P,P-diphenyl-N-(propan-2-ylidene)phosphinic amide, methyl 2-isocyanoacetate
Product:
5-substituted methyl (4R,5R)-1-(diphenylphosphoryl)-5-methyl-4,5-dihydro-1H-imidazole-4-carboxylate
Catalyst:
N-(9R)-cinchonan-9-yl-4-(trifluoromethyl)-2-Pyridinecarboxamide
Cas No:
1666132-24-6
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5