Stereoselective Organocatalyzed Synthesis of α‐Fluorinated β‐Amino Thioesters and Their Application in Peptide Synthesis.
DOI Number:
10.1002/anie.201607146
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
methyl 2-fluoro-3-((2-fluorophenyl)thio)-3-oxopropanoate, tert-butyl (E)-benzylidenecarbamate
Product:
methyl (2R,3S)-3-((tert-butoxycarbonyl)amino)-2-fluoro-2-(((2-fluorophenyl)thio)carbonyl)-3-phenylpropanoate
Catalyst:
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1352957-59-5
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7