Asymmetric Mannich reaction: Synthesis of novel chiral 5-(substituted aryl)-1, 3, 4-thiadiazole derivatives with anti-plant-virus potency.
DOI Number:
10.1515/hc-2019-0005
Reaction Category:
Educt:
5-(4-chlorophenyl)-1,3,4-thiadiazol-2-amine, 2,3-dichlorobenzaldehyde, diethyl malonate
Product:
diethyl 2-(((5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl)amino)(2,3-dichlorophenyl)-l3-methyl)malonate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0