Enantioselective organocatalytic anti-Mannich-type reaction of N-unprotected 3-substituted 2-oxindoles with aromatic N-Ts-aldimines.

DOI Number:

10.1021/jo9006688
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

3,5-disubstituted indolin-2-one, substituted (E)-N-tosylformimidoyl

Product:

N-((S)-substituted-((S)-3,5-disubstituted-2-oxoindolin-3-yl)methyl)-4-methylbenzenesulfonamide

Catalyst:

(8α,9R)-9-(9-phenanthrenyloxy)-cinchonan-6′-ol

Cas No:

844657-46-1

Associated Product from Buchler GmbH:

Cupreine Base

Cas No:

524-63-0