One-pot synthesis of optically active β-amino-α-methylene carbonyl derivatives from α-amidosulfones using quinine-based phase-transfer catalysts.

DOI Number:

10.1021/op1000308
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

1-(diphenylphosphoryl)propan-2-one, α-amidosulfones

Product:

β-amino-α-methylene carbonyl

Catalyst:

(8α,9R)-9-hydroxy-6′-methoxy-1-[(2-methoxyphenyl)methyl]-cinchonanium chloride

Cas No:

959964-92-2

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0