Enantioselective synthesis of (s)-afoxolaner and solid forms of (s)-afoxolaner.

DOI Number:

Reaction Category:

MOP ID:

MOP_0000561

Educt:

(Z)-4-(3-(3-chloro-5-(trifluoromethyl)phenyl)-4,4,4-trifluorobut-2-enoyl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide, hydroxylamine

Product:

(s)-afoxolaner

Catalyst:

(8α,9R)-9-hydroxy-6′-methoxy-1-[[3,4,5-tris[(4-methylphenyl)methyl]phenyl]methyl]-cinchonanium chloride

Cas No:

3125058-36-5

Cas No:

130-95-0