Catalyst-free and catalytic Friedel–Crafts alkylations of indoles in Solkane 365mfc, an environmentally benign alternative solvent.

DOI Number:

10.1039/c0gc00619j

Reaction Category:

RXNO ID:

RXNO_0000369

Educt:

7-methyl-1H-indole, ethyl 2-oxoacetate,

Product:

ethyl 2-hydroxy-2-(7-methyl-1H-indol-3-yl)-2lambda3-ethanoate

Catalyst:

9-[[4-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl) phenyl]methoxy]-(8α,9R)-Cinchonan-6′-ol

Cas No:

1265815-60-8

Cas No:

524-63-0