Organocatalytic enantioselective Friedel–Crafts aminoalkylation of indoles in the carbocyclic ring.
DOI Number:
10.1021/acscatal.6b00260
Reaction Category:
RXNO ID:
RXNO_0000369
Educt:
4-hydroxyindole, tert-butyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate
Product:
tert-butyl (R)-(3-(4-hydroxy-1H-indol-5-yl)-1-methyl-2-oxoindolin-3-yl)carbamate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0