Highly Enantioselective Monofluoromethylation of C2-Arylindoles Using FBSM under Chiral Phase-Transfer Catalysis.

DOI Number:

10.1021/ol4013102

Reaction Category:

MOP ID:

MOP_0000553

Educt:

2-aryl-3-(1-arylsulfonylmethyl)indoles, 1-fluoro-1,1-bis(phenylsulfonyl)methane

Product:

2-aryl-3-(2-fluoro-2,2-bis(phenylsulfonyl)ethyl)indoles

Catalyst:

1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-hydroxy-(9S)-Cinchonanium bromide (1:1)

Cas No:

1190864-60-8

Cas No:

118-10-5