Asymmetric Synthesis of Both Mirror Images of 3′-Fluorothalidomide by Enantiodivergent Fluorination Using a Single, Cinchona Alkaloid.
DOI Number:
10.1021/ol102818g
Reaction Category:
MOP ID:
MOP_0000553
Educt:
tert-butyl 3-(1,3-dioxoisoindolin-2-yl)-2-oxopiperidine-1-carboxylate, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide
Product:
tert-butyl (S)-3-(1,3-dioxoisoindolin-2-yl)-3-fluoro-2-oxopiperidine-1-carboxylate
Catalyst:
Dihydroquinine Base
Cas No:
522-66-7
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7