Recyclable fluorous cinchona alkaloid ester as a chiral promoter for asymmetric fluorination of β-ketoester.
DOI Number:
10.3762/bjoc.8.138
Reaction Category:
Educt:
ethyl 2-(1-benzyl-2,5-dioxopyrrolidin-3-yl)-3-oxo-3-phenylpropanoate, 1-(chloromethyl)-4-fluoro-1,4-Diazoniabicyclo[2.2.2]octane tetrafluoroborate
Product:
ethyl (S)-2-((S)-1-benzyl-2,5-dioxopyrrolidin-3-yl)-2-fluoro-3-oxo-3-phenylpropanoate
Catalyst:
(R)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl 4-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)benzoate
Cas No:
1456767-77-3
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0