Development of Enantioselective Fluorination Reaction and Its Application to the Synthesis of Biologically Active Compounds.

DOI Number:

10.5059/yukigoseikyokaishi.64.14

Reaction Category:

MOP ID:

MOP_0000553

Educt:

3-(5-chloro-2-methoxyphenyl)-6-(trifluoromethyl)indolin-2-one, 1-(chloromethyl)-4-fluoro-1,4-diazabicyclo[2.2.2]octane-1,4-diium

Product:

(S)-3-(5-chloro-2-methoxyphenyl)-3-fluoro-6-(trifluoromethyl)indolin-2-one (MaxiPost)

Catalyst:

1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]oxy]-9,10-Anthracenedione

Cas No:

176097-24-8

Cas No:

522-66-7