Asymmetric permanganate dihydroxylation of enoates: substrate scope, mechanistic insights and application in bicalutamide synthesis.
DOI Number:
10.1039/D3QO01729J
Reaction Category:
MOP ID:
MOP_0000673
Educt:
(E)-3-methyl-5-phenylpent-2-enoates, potassium permanganate
Product:
(2S,3R)-2,3-dihydroxy-3-methyl-5-phenylpentanoates
Catalyst:
(9S)-1-[[5-bromo-3′,5′-bis(trifluoromethyl)[1,1′-biphenyl]-3-yl]methyl]-9-[[3,3′′,5,5′′-tetrakis(1,1-dimethylethyl)[1,1′:3′,1′′-terphenyl]-5′-yl]methoxy]-cinchonanium bromide
Cas No:
2750373-63-6
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5