Efficient asymmetric synthesis of β-amino acid BAY 10-8888/PLD-118, a novel antifungal for the treatment of yeast infections.
DOI Number:
10.1055/s-2003-36265
Reaction Category:
Educt:
(3aR,6aS)-5-methylenetetrahydro-1H-cyclopenta[c]furan-1,3(3aH)-dione, (E)-3-phenylprop-2-en-1-ol
Product:
(1S,2R)-2-((cinnamyloxy)carbonyl)-4-methylenecyclopentane-1-carboxylic acid
Catalyst:
Quinine Base
Cas No:
130-95-0
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0