Organocatalyzed Enantioselective Decarboxylative Mannich Reaction of β-Ketoacids with Pyrazolinone Ketimines for the Construction of Chiral β-Amino Ketone-Pyrazolinone Derivatives.
DOI Number:
10.1002/ejoc.201900346
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
tert-butyl (Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)carbamate, 3-(4-fluorophenyl)-3-oxopropanoic acid
Product:
tert-butyl (S)-(4-(2-(4-fluorophenyl)-2-oxoethyl)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)carbamate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0