Organocatalyzed Asymmetric Formal [3+2] Cycloaddition between Cyclic Nitrones and Meldrum’s Acid for the Formal Total Synthesis of (−)-Crispine A.

DOI Number:

10.1021/acs.joc.6c01394
Link to literature

Reaction Category:

[3+2]-Cycloaddition | Cycloaddition

MOP ID:

MOP_0000715

Educt:

cyclic nitrones, meldrum’s acid

Product:

substituted isoxazolidinone

Catalyst:

N-[(8α,9S)-6′-methoxycinchonan-9-yl]-N′-[4-(trifluoromethyl)phenyl]-urea

Cas No:

2226221-24-3

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0